People who are successfully boondocking may start thinking about going full-time (FT). IMO anyone who is comfortably making 14d outings can do it FT.

There are a few things that will change

We are not allowed to live on public lands. We are allowed to recreate or camp according to the rules, then move on according to the rules. Remember this when speaking to rangers or LEOs.

A rig that is barely making 14d on water, food, etc, should be addressed. You could get caught behind a washed-out bridge, waterlogged roads, etc, and be incapable of getting out to resupply in time.

If your battery bank is on 0% when you get home and requires shore power charging to catch up then charging needs to be augmented.

Since you no longer have a home base some form of mail forwarding will be required. It common to have one's mail sent General Delivery to the nearest post office.